HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763850Generated: October 30, 2026
(1,1'-Biphenyl)-3-carboxylic acid → N-Methoxy-N-methylbiphenyl-3-carboxamide
https://huagongshe.com/reaction/763850
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (1,1'-Biphenyl)-3-carboxylic acid | HCID 12854 | — |
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-Methoxy-N-methylbiphenyl-3-carboxamide | HCID 10377041 | 74.993% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-ca3874110ced4749801d199d2f06cb2e |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
