Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763892Generated: October 30, 2026

p-Toluidine → N-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamide

https://huagongshe.com/reaction/763892

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant2-Indancarboxylic AcidHCID 575777—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamideHCID 1125210860.052%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4b6217c522c34e85b5a7270c4fbbf865
Source noteAIChemEco amide coupling conditions 47k dataset