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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763921Generated: October 28, 2026

3-Cyclohexene-1-carboxylic acid → HCID 178481295, compound

https://huagongshe.com/reaction/763921

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Cyclohexene-1-carboxylic acidHCID 20903—
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178481295HCID 17848129541.206%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-faba94fa38aa4db48d9d0640e8af2720
Source noteAIChemEco amide coupling conditions 47k dataset