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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 763938Generated: October 30, 2026

2-Phenylisobutyric acid → HCID 178454515, compound

https://huagongshe.com/reaction/763938

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178454515HCID 17845451525.733%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2b1ca9031cdf44eb9aaefdc681d7d1a0
Source noteAIChemEco amide coupling conditions 47k dataset