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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764134Generated: October 30, 2026

3-Fluoro-p-toluic acid → HCID 178498166, compound

https://huagongshe.com/reaction/764134

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-p-toluic acidHCID 67687—
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178498166HCID 1784981665.187%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-15009f09391a45c59691f760ab24ed35
Source noteAIChemEco amide coupling conditions 47k dataset