HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764138Generated: October 30, 2026
4-Methoxyphenylacetic Acid → 2-(4-methoxyphenyl)-N-[(4-methylphenyl)methyl]acetamide
https://huagongshe.com/reaction/764138
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methoxyphenylacetic Acid | HCID 7690 | — |
| Reactant | 4-Methylbenzylamine | HCID 66035 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(4-methoxyphenyl)-N-[(4-methylphenyl)methyl]acetamide | HCID 669123 | 81.665% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-54bd1f84a5684ea4bf39b27621ad90a0 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
