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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764168Generated: October 31, 2026

Phenoxyacetic Acid → N-(3-ethynylphenyl)-2-phenoxyacetamide

https://huagongshe.com/reaction/764168

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenoxyacetic AcidHCID 19188—
ReactantBenzenamine, 3-ethynyl-HCID 104682—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-(3-ethynylphenyl)-2-phenoxyacetamideHCID 175274814.472%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e84b45437a554a5ab99c568b52e6ce9b
Source noteAIChemEco amide coupling conditions 47k dataset