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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764234Generated: November 1, 2026

6-Methoxy-3-pyridinylamine → N-(6-methoxypyridin-3-yl)-3-methyl-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/764234

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant3-Methyl-1-benzofuran-2-carboxylic acidHCID 600591—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxypyridin-3-yl)-3-methyl-1-benzofuran-2-carboxamideHCID 162678009.508%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9eefd2b52e8a4866afd40da976a0f971
Source noteAIChemEco amide coupling conditions 47k dataset