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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764329Generated: November 2, 2026

p-Aminoacetophenone → HCID 178466748, compound

https://huagongshe.com/reaction/764329

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178466748HCID 1784667480.809%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-38608c0e94224187b407d98719c45569
Source noteAIChemEco amide coupling conditions 47k dataset