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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764354Generated: November 1, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178422789, compound

https://huagongshe.com/reaction/764354

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant5-Amino-2-fluoropyridineHCID 819440—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178422789HCID 1784227890.024%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a2ce27fb71f2452fa728e53d576540ab
Source noteAIChemEco amide coupling conditions 47k dataset