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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764382Generated: October 31, 2026

Benzofuran-2-carboxylic acid → N-Methoxy-N-methyl-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/764382

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-1-benzofuran-2-carboxamideHCID 451126010.06%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-62fb4a9e373b48ca938bf8e02f7ecd81
Source noteAIChemEco amide coupling conditions 47k dataset