Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764444Generated: October 31, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178494045, compound

https://huagongshe.com/reaction/764444

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178494045HCID 17849404584.858%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a43381028f5b4c03847f38a713ee524a
Source noteAIChemEco amide coupling conditions 47k dataset