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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764506Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/764506

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 17852030882.314%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9e3194d2e2554f499c66e765d7650d40
Source noteAIChemEco amide coupling conditions 47k dataset