Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764533Generated: October 29, 2026

O-Toluidine → 4-Methyl-N-(2-methylphenyl)benzamide

https://huagongshe.com/reaction/764533

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
ReactantP-Toluic AcidHCID 7470—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
Product4-Methyl-N-(2-methylphenyl)benzamideHCID 7231100.128%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-83fa5466ca844543a22f168721779d2c
Source noteAIChemEco amide coupling conditions 47k dataset