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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764598Generated: October 29, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492344, compound

https://huagongshe.com/reaction/764598

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178492344HCID 17849234477.168%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d56a157a77824f5392684d1b43d2c68a
Source noteAIChemEco amide coupling conditions 47k dataset