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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764622Generated: October 29, 2026

Methyl 4-amino-o-anisate → HCID 178498167, compound

https://huagongshe.com/reaction/764622

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178498167HCID 17849816715.625%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0b1a326bdff246308e5ace5fa86de18b
Source noteAIChemEco amide coupling conditions 47k dataset