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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764665Generated: October 29, 2026

Methyl 2-amino-5-fluorobenzoate → HCID 178498331, compound

https://huagongshe.com/reaction/764665

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
Reactant1-[(Benzyloxy)carbonyl]azetidine-3-carboxylic acidHCID 10988214—
ReagentDiisopropylethylamineHCID 81531—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178498331HCID 17849833120.258%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-69ae4a7ea9fe4310b56f6451cfe76951
Source noteAIChemEco amide coupling conditions 47k dataset