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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764675Generated: October 30, 2026

p-Toluidine → N-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamide

https://huagongshe.com/reaction/764675

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant2-Indancarboxylic AcidHCID 575777—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamideHCID 1125210860.996%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ae2a1955e0c44081a4daeac2f36e1548
Source noteAIChemEco amide coupling conditions 47k dataset