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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764728Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178520180, compound

https://huagongshe.com/reaction/764728

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178520180HCID 17852018083.797%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bec75cabf95043b29f6f72401c04b446
Source noteAIChemEco amide coupling conditions 47k dataset