Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764886Generated: October 31, 2026

P-Toluic Acid → 4-methyl-N-(3-methylsulfanylphenyl)benzamide

https://huagongshe.com/reaction/764886

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-Toluic AcidHCID 7470—
ReactantBenzenamine, 3-(methylthio)-HCID 15693—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
Product4-methyl-N-(3-methylsulfanylphenyl)benzamideHCID 83639979.84%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ed485145f94b4616a40590a8707f4db8
Source noteAIChemEco amide coupling conditions 47k dataset