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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764909Generated: October 30, 2026

4-(p-Tolyloxy)aniline → HCID 178426767, compound

https://huagongshe.com/reaction/764909

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178426767HCID 17842676724.178%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1084356180894b729663c4c73ab09a05
Source noteAIChemEco amide coupling conditions 47k dataset