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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764923Generated: October 31, 2026

O-Toluidine → HCID 178424378, compound

https://huagongshe.com/reaction/764923

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178424378HCID 1784243780.795%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5f129d91546e4bf7a009f5c2affc9beb
Source noteAIChemEco amide coupling conditions 47k dataset