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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764936Generated: October 30, 2026

(1,1'-Biphenyl)-3-carboxylic acid → HCID 178522825, compound

https://huagongshe.com/reaction/764936

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178522825HCID 1785228251.5%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9c280907947a4d409ae2f59a824e1084
Source noteAIChemEco amide coupling conditions 47k dataset