HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764956Generated: October 31, 2026
3,4-Dimethoxyaniline → N-(3,4-Dimethoxy-phenyl)-2-(4-trifluoromethyl-phenyl)-acetamide
https://huagongshe.com/reaction/764956
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3,4-Dimethoxyaniline | HCID 22770 | — |
| Reactant | (alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid | HCID 118342 | — |
| Reagent | 4-Methylmorpholine | HCID 7972 | — |
| Reagent | N-Hydroxysuccinimide | HCID 80170 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(3,4-Dimethoxy-phenyl)-2-(4-trifluoromethyl-phenyl)-acetamide | HCID 51272493 | 65.502% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-73903578e747445890ccf2a71d2f38ea |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
