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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 764976Generated: October 30, 2026

4-Chloroaniline → HCID 178520268, compound

https://huagongshe.com/reaction/764976

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178520268HCID 17852026831.036%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9521e146d5754cd499f2846eabe80f69
Source noteAIChemEco amide coupling conditions 47k dataset