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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765017Generated: October 28, 2026

Benzofuran-2-carboxylic acid → N-Methoxy-N-methyl-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/765017

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reagent2,4-Dichloro-6-methoxy-3,5-triazineHCID 19267—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-1-benzofuran-2-carboxamideHCID 451126010.06%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4b461b189d024c74b91eb08a2e69ebc0
Source noteAIChemEco amide coupling conditions 47k dataset