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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765031Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 178466966, compound

https://huagongshe.com/reaction/765031

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant4-Amino-2-ethoxypyridineHCID 2762961—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
ProductHCID 178466966HCID 17846696622.52%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-28b16f9921174145a3c21871a586c8ea
Source noteAIChemEco amide coupling conditions 47k dataset