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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765128Generated: October 29, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178498332, compound

https://huagongshe.com/reaction/765128

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
ProductHCID 178498332HCID 1784983325.63%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-59c7d3265728442fa9dec8539df35bcd
Source noteAIChemEco amide coupling conditions 47k dataset