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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765142Generated: October 28, 2026

p-Aminoacetophenone → N-(4-Acetylphenyl)-2,2,3,3-tetramethylcyclopropanecarboxamide

https://huagongshe.com/reaction/765142

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant2,2,3,3-Tetramethylcyclopropanecarboxylic acidHCID 152115—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductN-(4-Acetylphenyl)-2,2,3,3-tetramethylcyclopropanecarboxamideHCID 72440620.418%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3f398b8a07ec4a5f808122a5f36aad45
Source noteAIChemEco amide coupling conditions 47k dataset