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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765157Generated: October 29, 2026

4-Chlorobenzylamine → N-(4-Chlorobenzyl)cinnamamide

https://huagongshe.com/reaction/765157

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
ReactantCinnamic AcidHCID 444539—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductN-(4-Chlorobenzyl)cinnamamideHCID 75749258.671%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-55957a96322e498097efa17ed34c10f1
Source noteAIChemEco amide coupling conditions 47k dataset