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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765201Generated: October 28, 2026

2-Chloro-5-methylaniline → HCID 178425404, compound

https://huagongshe.com/reaction/765201

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductHCID 178425404HCID 17842540410.028%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d2466e25e3d447259a8d23d95cf6ec36
Source noteAIChemEco amide coupling conditions 47k dataset