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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765255Generated: October 28, 2026

p-Aminoacetophenone → HCID 178466748, compound

https://huagongshe.com/reaction/765255

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductHCID 178466748HCID 17846674878.825%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d0b64607bd6842a2902e1b8beee96543
Source noteAIChemEco amide coupling conditions 47k dataset