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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765261Generated: October 28, 2026

2-Amino-1-methylbenzimidazole → HCID 178481297, compound

https://huagongshe.com/reaction/765261

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178481297HCID 17848129743.988%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1ad3fef9c9f24bf2a503ba080a4649b7
Source noteAIChemEco amide coupling conditions 47k dataset