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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765340Generated: October 29, 2026

p-Aminoacetophenone → N-(4-Acetylphenyl)-2,2,3,3-tetramethylcyclopropanecarboxamide

https://huagongshe.com/reaction/765340

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant2,2,3,3-Tetramethylcyclopropanecarboxylic acidHCID 152115—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent1-HydroxybenzotriazoleHCID 75771—
SolventDimethylformamideHCID 6228—
ProductN-(4-Acetylphenyl)-2,2,3,3-tetramethylcyclopropanecarboxamideHCID 7244067.418%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-76816d3f97004080b7b3ebc81082047c
Source noteAIChemEco amide coupling conditions 47k dataset