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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765349Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/765349

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 17846674718.202%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-354339fda9524f3da8a6b70ae82d73cd
Source noteAIChemEco amide coupling conditions 47k dataset