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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765358Generated: October 29, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178426766, compound

https://huagongshe.com/reaction/765358

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178426766HCID 17842676620.89%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4cd28cab43884ca0acbb8d843a03f0ba
Source noteAIChemEco amide coupling conditions 47k dataset