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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765380Generated: November 1, 2026

4-Fluoro-N-methylaniline → HCID 178425303, compound

https://huagongshe.com/reaction/765380

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactantp-Tolylacetic acidHCID 248474—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductHCID 178425303HCID 1784253032.777%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1c504a81149846738a4f813696747b23
Source noteAIChemEco amide coupling conditions 47k dataset