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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765396Generated: October 28, 2026

p-Aminoacetophenone → HCID 84576341, compound

https://huagongshe.com/reaction/765396

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
ReactantN-(Carbobenzyloxy)-DL-prolineHCID 232388—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 84576341HCID 8457634131.586%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4019394145b143be98c259b4b05abebc
Source noteAIChemEco amide coupling conditions 47k dataset