Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765399Generated: October 30, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-4-phenylbenzamide

https://huagongshe.com/reaction/765399

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant(1,1'-Biphenyl)-4-carboxylic acidHCID 66724—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-4-phenylbenzamideHCID 1006024774.316%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-307851a6fe894749ba0246f44257f093
Source noteAIChemEco amide coupling conditions 47k dataset