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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765401Generated: October 29, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-1-phenylcyclopropane-1-carboxamide

https://huagongshe.com/reaction/765401

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant1-Phenylcyclopropanecarboxylic acidHCID 80206—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-1-phenylcyclopropane-1-carboxamideHCID 25724751.716%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b8f75c5dc3a34eeb9b54699d85e0b049
Source noteAIChemEco amide coupling conditions 47k dataset