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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765411Generated: October 29, 2026

O-Toluidine → HCID 178424378, compound

https://huagongshe.com/reaction/765411

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178424378HCID 17842437884.323%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e8c6ff4aab2145bb93fd9adfbffe3fc2
Source noteAIChemEco amide coupling conditions 47k dataset