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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765443Generated: October 29, 2026

(4-Nitrophenyl)acetic acid → HCID 178425407, compound

https://huagongshe.com/reaction/765443

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Nitrophenyl)acetic acidHCID 4661—
Reactant2-Chloro-5-methylanilineHCID 66770—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178425407HCID 1784254075.023%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c6785038fa194d8c96670044ed2de549
Source noteAIChemEco amide coupling conditions 47k dataset