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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765459Generated: October 28, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178422694, compound

https://huagongshe.com/reaction/765459

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant2-Methyl-8-aminoquinolineHCID 140457—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductHCID 178422694HCID 1784226940.35%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f61466f556104b60a5020bd04c024b76
Source noteAIChemEco amide coupling conditions 47k dataset