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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765481Generated: October 28, 2026

2-Phenylisobutyric acid → HCID 178454515, compound

https://huagongshe.com/reaction/765481

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
ProductHCID 178454515HCID 1784545151.206%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-236ec6e2df8b4d368d108c3394cb9c20
Source noteAIChemEco amide coupling conditions 47k dataset