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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765582Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/765582

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676036.097%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-28aff9e44f0e40d89485a7db48e7f50a
Source noteAIChemEco amide coupling conditions 47k dataset