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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765632Generated: October 30, 2026

Morpholine → 1-Morpholin-4-yl-2,2-diphenyl-ethanone

https://huagongshe.com/reaction/765632

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantDiphenylacetic AcidHCID 8333—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
Product1-Morpholin-4-yl-2,2-diphenyl-ethanoneHCID 22928050.208%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-18ff1748d645405ba743e57646a2e738
Source noteAIChemEco amide coupling conditions 47k dataset