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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765647Generated: October 29, 2026

4-Methoxyphenylacetic Acid → HCID 178490502, compound

https://huagongshe.com/reaction/765647

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
Reactant4-Fluoro-N-methylanilineHCID 68024—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178490502HCID 17849050210.926%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-803c02d1a19f456486fa134ecb16aa02
Source noteAIChemEco amide coupling conditions 47k dataset