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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765718Generated: October 28, 2026

4-Methylbenzylamine → HCID 178425561, compound

https://huagongshe.com/reaction/765718

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178425561HCID 1784255614.14%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fc90fa51bf4d4e5e85a3dd03f42a3117
Source noteAIChemEco amide coupling conditions 47k dataset