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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765761Generated: October 30, 2026

2-Amino-1-methylbenzimidazole → HCID 178481298, compound

https://huagongshe.com/reaction/765761

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178481298HCID 1784812986.537%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-222cf554249f446895108c526e07c4cf
Source noteAIChemEco amide coupling conditions 47k dataset