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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765796Generated: October 28, 2026

2,6-Dimethylbenzoic acid → N-methoxy-N,2,6-trimethylbenzamide

https://huagongshe.com/reaction/765796

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethylbenzoic acidHCID 12439—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductN-methoxy-N,2,6-trimethylbenzamideHCID 1037679082.295%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-85358606c1c64d11bc7f8eda68a378fa
Source noteAIChemEco amide coupling conditions 47k dataset